Technical Specifications: iPod nano
1GB, 2GB or 4GB flash drive(1)
Holds 240 to 1,000 songs in 128-Kbps AAC format(2)
Holds 15,000 to 25,000 iPod nano-viewable photos(2)
Stores data via USB flash drive
According to that, you should be able to transfer files pretty easy however its not specificly saying that software isnt needed. Personally i wouldnt think so, generally a flash drive works from a mass storage device driver thats implemented into XP already.