Hi lotusblossom, I've had the same problem with my Logitech cordless mousey (and man is it annoying!). Before you get your screwdriver out take a look at -
http://www.ntcompatible.com/Fix_for_Sti ... t8816.html .
After spotting this, I switched my cordless mousey receiver from USB to the pin socket*, and after a restart the problem has not reappeared!
*through the adaptor they kindly supplied
The link gives some commenary on what is going wrong and why the changeover should work. If you are running yours through the USB port then this may work for you!
Best of luck, let us know how you get on.
Just Kev